Chiral phosphoric acid-catalyzed oxidative kinetic resolution of indolines based on transfer hydrogenation to imines.

نویسندگان

  • Kodai Saito
  • Yukihiro Shibata
  • Masahiro Yamanaka
  • Takahiko Akiyama
چکیده

The oxidative kinetic resolution of 2-substituted indoline derivatives was achieved by hydrogen transfer to imines by means of a chiral phosphoric acid catalyst. The oxidative kinetic resolution was applicable to racemic alkyl- or aryl-substituted indolines, and the remaining indolines were obtained in good yields with excellent enantioselectivities.

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عنوان ژورنال:
  • Journal of the American Chemical Society

دوره 135 32  شماره 

صفحات  -

تاریخ انتشار 2013